TDRD5 antibody

Catalogue No.:FNab08579Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TDRD5 antibody
Catalogue No.
FNab08579
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
tudor domain containing 5
UniProt ID
Q8NAT2
Observed MW
116 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08579(TDRD5 Antibody) at dilution of 1:300
IP Result of anti-TDRD5 (IP:FNab08579, 5ug; Detection:FNab08579 1:300) with mouse testis tissue lysate 2800ug.
Immunohistochemistry of paraffin-embedded mouse testis tissue slide using FNab08579(TDRD5 Antibody) at dilution of 1:50
Background
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body(CB) assembly(By similarity).