Products
TDRD3 antibody
- Product Name
- TDRD3 antibody
- Catalogue No.
- FNab08578
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tudor domain containing 3
- UniProt ID
- Q9H7E2
- Observed MW
- 73 kDa; 83 kDa
Application
- Tested Applications
- ELISA, WB, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08578(TDRD3 Antibody) at dilution of 1:300
IP Result of anti-TDRD3 (IP:FNab08578, 3ug; Detection:FNab08578 1:1000) with HeLa cells lysate 3800ug.
- Background
- Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation(H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs(GAR) in dimethylarginine-containing proteins.
