Products

anti- TCEB3 antibody

FNab08550 Catalogue No.
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Isotype:
IgG
Tested Application:
ELISA, WB, IHC, IF
Product Information
Product Name
anti- TCEB3 antibody
Catalogue No.
FNab08550
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Immunogen Information
Immunogen
transcription elongation factor B (SIII) , polypeptide 3 (110kDa, elongin A)
Observed MW
105 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Uniprot information
UniProt ID
Q14241
Images
Immunohistochemistry of paraffin-embedded human kidney cancer using FNab08550 (TCEB3 antibody) at dilution of 1:100
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08550 (TCEB3 antibody) at dilution of 1:1000