human liver tissue were subjected to SDS PAGE followed by western blot with FNab08547(TCEAL7 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab08547(TCEAL7 antibody) at dilution of 1:50
Background
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT(alternative lengthening of telomeres)and telomerase-positive cell lines.