Products

TBP antibody

Synonyms:GTF2D1 antibody, TF2D antibody, TFIID antibody
Catalogue No.:FNab08526Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TBP antibody
Catalogue No.
FNab08526
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
TATA box binding protein
Alternative Names
GTF2D1 antibody, TF2D antibody, TFIID antibody
UniProt ID
P20226
Observed MW
human 37-43kDa
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08526(TBP antibody) at dilution of 1:1000
Background
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.