HeLa cells were subjected to SDS PAGE followed by western blot with FNab08517(TBCB antibody) at dilution of 1:500
IP Result of anti-TBCB (IP:FNab08517, 3ug; Detection:FNab08517 1:500) with HeLa cells lysate 1200ug.
Background
Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.