Products

anti- TBC1D17 antibody

FNab08510 Catalogue No.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IF, IHC
Product Information
Product Name
anti- TBC1D17 antibody
Catalogue No.
FNab08510
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
Immunogen Information
Immunogen
TBC1 domain family, member 17
Observed MW
73 kDa
Application
Tested Application
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Uniprot information
UniProt ID
Q9HA65
Images
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08510(TBC1D17 Antibody) at dilution of 1:50
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08510(TBC1D17 antibody) at dilution of 1:1000