HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08506(TAX1BP1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab08506( TAX1BP1 Antibody) at dilution of 1:100
Background
TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa.