Products
TAOK3 antibody
- Product Name
- TAOK3 antibody
- Catalogue No.
- FNab08498
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TAO kinase 3
- Alternative Names
- DPK antibody, JIK antibody, KDS antibody, MAP3K18 antibody
- UniProt ID
- Q9H2K8
- Observed MW
- 100-105 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab08498(TAOK3 antibody) at dilution of 1:800
IP Result of anti-TAOK3 (IP:FNab08498, 4ug; Detection:FNab08498 1:700) with HepG2 cells lysate 3600ug.
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab08498(TAOK3 Antibody) at dilution of 1:200
- Background
- Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor(EGF).
