Products
TALPID3 antibody
- Product Name
- TALPID3 antibody
- Catalogue No.
- FNab08496
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- KIAA0586
- UniProt ID
- E9PV87
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:50-1:500
Validated Images
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab08496( TALPID3 antibody) at dilution of 1:200
- Background
- Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).
