HeLa cells were subjected to SDS PAGE followed by western blot with FNab08481(TAF1B antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human testis using FNab08481(TAF1B antibody) at dilution of 1:200
Background
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex(PIC) assembly and postpolymerase recruitment events in polymerase I(Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.