L02 cells were subjected to SDS PAGE followed by western blot with FNab08465(TAB2 antibody) at dilution of 1:2000
IP Result of anti-TAB2 (IP:FNab08465, 4ug; Detection:FNab08465 1:600) with HepG2 cells lysate 3600ug.
Immunohistochemistry of paraffin-embedded human malignant melanoma using FNab08465(MAP3K7IP2 antibody) at dilution of 1:100
Background
Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.