Products
SYTL2 antibody
- Product Name
- SYTL2 antibody
- Catalogue No.
- FNab08460
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- synaptotagmin-like 2
- Alternative Names
- KIAA1597 antibody, SGA72M antibody, SLP2 antibody, SLP2A antibody
- UniProt ID
- Q9HCH5
- Observed MW
- 100-105 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08460(SYTL2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab08460(SYTL2 antibody) at dilution of 1:50
- Background
- Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine(PS) and phosphatidylinositol-4,5-bisphosphate(PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
