Products
SYNM antibody
- Product Name
- SYNM antibody
- Catalogue No.
- FNab08440
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- synemin, intermediate filament protein
- Alternative Names
- DMN antibody, KIAA0353 antibody, SYN antibody
- UniProt ID
- O15061
- Observed MW
- 175 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
Y79 cells were subjected to SDS PAGE followed by western blot with FNab08440(SYNM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human skeletal muscle using FNab08440(SYNM antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab08440 (SYNM antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Background
- Type-VI intermediate filament(IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
