Products
SUPV3L1 antibody
- Product Name
- SUPV3L1 antibody
- Catalogue No.
- FNab08397
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- suppressor of var1, 3-like 1
- Alternative Names
- SUV3 antibody
- UniProt ID
- Q8IYB8
- Observed MW
- 70-80 kDa
Application
- Tested Applications
- ELISA, IP, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08397(SUPV3L1 Antibody) at dilution of 1:600
IP Result of anti-SUPV3L1 (IP:FNab08397, 4ug; Detection:FNab08397 1:300) with HeLa cells lysate 1200ug.
- Background
- Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome(mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded(ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
