K-562 cells were subjected to SDS PAGE followed by western blot with FNab08360(STXBP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08360(STXBP2 antibody) at dilution of 1:100
Background
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.