STOML2 antibody

Synonyms:SLP2 antibody
Catalogue No.:FNab08346Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IF, IP, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
STOML2 antibody
Catalogue No.
FNab08346
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
stomatin(EPB72)-like 2
Alternative Names
SLP2 antibody
UniProt ID
Q9UJZ1
Observed MW
39 kDa
Application
Tested Applications
ELISA, IHC, IF, IP, WB
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
C6 cells were subjected to SDS PAGE followed by western blot with FNab08346(STOML2 Antibody) at dilution of 1:1000
IP Result of anti-STOML2 (IP:FNab08346, 3ug; Detection:FNab08346 1:1000) with mouse brain tissue lysate 1000ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08346(STOML2 antibody) at dilution of 1:100
Background
Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.