Products
STIM2 antibody
- Product Name
- STIM2 antibody
- Catalogue No.
- FNab08322
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- stromal interaction molecule 2
- Alternative Names
- KIAA1482 antibody
- UniProt ID
- Q9P246
- Observed MW
- 85-115 kDa
Application
- Tested Applications
- ELISA, IHC, IP, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08322(STIM2 Antibody) at dilution of 1:1000
IP Result of anti-STIM2 (IP:FNab08322, 3ug; Detection:FNab08322 1:500) with HEK-293 cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human spleen tissue slide using FNab08322(STIM2 Antibody) at dilution of 1:200
- Background
- Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+)(CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
