Products
ST5 antibody
- Product Name
- ST5 antibody
- Catalogue No.
- FNab08268
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- suppression of tumorigenicity 5
- Alternative Names
- DENND2B antibody, HTS1 antibody
- UniProt ID
- P78524
- Observed MW
- 82 kDa,70 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab08268(ST5 antibody) at dilution of 1:500
- Background
- Guanine nucleotide exchange factor(GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.
