MCF-7 were subjected to SDS PAGE followed by western blot with FNab08228( SRI Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab08228(SRI antibody) at dilution of 1:50
Background
This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.