Products
SRA1 antibody
- Product Name
- SRA1 antibody
- Catalogue No.
- FNab08213
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- steroid receptor RNA activator 1
- Alternative Names
- pp7684 antibody, SRA antibody, SRA1 antibody, SRAP antibody, STRAA1 antibody
- UniProt ID
- Q9HD15
- Observed MW
- 30 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab08213(SRA1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08213(SRA1 Antibody) at dilution of 1:50
- Background
- Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain(AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain(AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
