SPTBN1-Specific antibody

Synonyms:Beta II spectrin antibody, beta-fodrin antibody, betaSpII antibody, ELF antibody, Fodrin beta chain antibody, Spectrin beta chain antibody, brain 1 antibody, SPTB2 antibody, SPTBN1 antibody
Catalogue No.:FNab08204Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SPTBN1-Specific antibody
Catalogue No.
FNab08204
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
spectrin, beta, non-erythrocytic 1
Alternative Names
Beta II spectrin antibody, beta-fodrin antibody, betaSpII antibody, ELF antibody, Fodrin beta chain antibody, Spectrin beta chain antibody, brain 1 antibody, SPTB2 antibody, SPTBN1 antibody
UniProt ID
Q01082
Observed MW
275 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:5000; IP:1:200-1:2000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08204(SPTBN1-Specific antibody) at dilution of 1:300
IP Result of anti-SPTBN1-Specific (IP:FNab08204, 5ug; Detection:FNab08204 1:600) with HEK-293 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human lung using FNab08204(SPTBN1-Specific antibody) at dilution of 1:100
Background
SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.