SPAM1 antibody

Synonyms:SPAM1 antibody, HEL-S-96n antibody, HYA1 antibody, HYAL1 antibody, HYAL3 antibody, HYAL5 antibody, PH-20 antibody, PH20 antibody, SPAG15 antibody, hyaluronidase PH-20 antibody
Catalogue No.:FNab08148Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SPAM1 antibody
Catalogue No.
FNab08148
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
sperm adhesion molecule 1(PH-20 hyaluronidase, zona pellucida binding)
Alternative Names
SPAM1 antibody, HEL-S-96n antibody, HYA1 antibody, HYAL1 antibody, HYAL3 antibody, HYAL5 antibody, PH-20 antibody, PH20 antibody, SPAG15 antibody, hyaluronidase PH-20 antibody
UniProt ID
P38567
Observed MW
50 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab08148(SPAM1 antibody) at dilution of 1:1000
Background
Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.