SOX7 antibody

Catalogue No.:FNab08129Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SOX7 antibody
Catalogue No.
FNab08129
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
SRY(sex determining region Y)-box 7
UniProt ID
Q9BT81
Observed MW
42-45 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08129(SOX7 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab08129(SOX7 Antibody) at dilution of 1:50
Background
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors(By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification(By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter(By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.