Products
SOX2 antibody
- Product Name
- SOX2 antibody
- Catalogue No.
- FNab08125
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SRY(sex determining region Y)-box 2
- Alternative Names
- ANOP3 antibody, MCOPS3 antibody, SOX2 antibody, Transcription factor SOX 2 antibody
- UniProt ID
- P48431
- Observed MW
- 34kd
Application
- Tested Applications
- ELISA, IF, WB, IHC
- Recommended dilution
- WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:500
Validated Images
U-251 cells were subjected to SDS PAGE followed by western blot with FNab08125(SOX2 antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human lung cancer tissue using FNab08125(SOX2 Antibody) at dilution of 1:100
Immunofluorescent analysis of ( 4% PFA ) fixed mouse embryo tissue using FNab08125 ( SOX2 Antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Background
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).
