SNRPB antibody

Synonyms:COD antibody, SNRPB1 antibody
Catalogue No.:FNab08070Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SNRPB antibody
Catalogue No.
FNab08070
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
small nuclear ribonucleoprotein polypeptides B and B1
Alternative Names
COD antibody, SNRPB1 antibody
UniProt ID
P14678
Observed MW
25-30 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08070(SNRPB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab08070(SNRPB Antibody) at dilution of 1:50
Background
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.