Products
SNCB antibody
- Product Name
- SNCB antibody
- Catalogue No.
- FNab08062
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- synuclein, beta
- Alternative Names
- Beta synuclein antibody, SNCB antibody, synuclein antibody, beta antibody, SYUB antibody
- UniProt ID
- Q16143
- Observed MW
- 14-18 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, FC
- Recommended dilution
- WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:10-1:100; IF: 1:10-1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08062(SNCB antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human breast cancer using FNab08062(SNCB antibody) at dilution of 1:10
- Background
- Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine(6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
