Products
SMYD3 antibody
- Product Name
- SMYD3 antibody
- Catalogue No.
- FNab08049
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SET and MYND domain containing 3
- Alternative Names
- ZMYND1 antibody, ZNFN3A1 antibody
- UniProt ID
- Q9H7B4
- Observed MW
- 42-45 kDa
Application
- Tested Applications
- ELISA, IHC, IP, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08049(SMYD3 antibody) at dilution of 1:800
IP Result of anti-SMYD3 (IP:FNab08049, 4ug; Detection:FNab08049 1:500) with COLO 320 cells lysate 1280ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab08049(SMYD3 antibody) at dilution of 1:50
- Background
- Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di-and tri-methylation, but not monomethylation(PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4(PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex(PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences(PubMed:15235609).
