HeLa cells were subjected to SDS PAGE followed by western blot with FNab08021( SMCHD1 Antibody) at dilution of 1:600
Background
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B(By similarity). Required for DUX4 silencing in somatic cells.