Products
SMC3 antibody
- Product Name
- SMC3 antibody
- Catalogue No.
- FNab08017
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- structural maintenance of chromosomes 3
- Alternative Names
- BAM antibody, BMH antibody, CSPG6 antibody, SMC3L1 antibody
- UniProt ID
- Q9UQE7
- Observed MW
- 140 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08017(SMC3 antibody) at dilution of 1:300
- Background
- Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
