Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07990(SLU7 antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using FNab07990(SLU7 antibody) at dilution of 1:50
Background
Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.