Products
SH3PXD2A antibody
- Product Name
- SH3PXD2A antibody
- Catalogue No.
- FNab07836
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SH3 and PX domains 2A
- Alternative Names
- FISH antibody, KIAA0418 antibody, SH3MD1 antibody, TKS5 antibody
- UniProt ID
- Q5TCZ1
- Observed MW
- 140 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07836(SH3PXD2A antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab07836(SH3PXD2A antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells using FNab07836 (SH3PXD2A antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Background
- Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
