K-562 cells were subjected to SDS PAGE followed by western blot with FNab07821(SH2D2A antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human heart using FNab07821(SH2D2A antibody) at dilution of 1:50
Background
Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.