Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07807(SGK2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using FNab07807(SGK2 Antibody) at dilution of 1:200
Background
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.