SF3A3 antibody

Synonyms:SAP61 antibody
Catalogue No.:FNab07776Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SF3A3 antibody
Catalogue No.
FNab07776
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
splicing factor 3a, subunit 3, 60kDa
Alternative Names
SAP61 antibody
UniProt ID
Q12874
Observed MW
59 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab07776(SF3A3 antibody) at dilution of 1:300
IP Result of anti-SF3A3 (IP:FNab07776, 4ug; Detection:FNab07776 1:600) with Raji cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab07776(SF3A3 antibody) at dilution of 1:50
Background
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.