Raji cells were subjected to SDS PAGE followed by western blot with FNab07776(SF3A3 antibody) at dilution of 1:300
IP Result of anti-SF3A3 (IP:FNab07776, 4ug; Detection:FNab07776 1:600) with Raji cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab07776(SF3A3 antibody) at dilution of 1:50
Background
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.