SF3A2 antibody

Synonyms:SAP62 antibody
Catalogue No.:FNab07775Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SF3A2 antibody
Catalogue No.
FNab07775
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
splicing factor 3a, subunit 2, 66kDa
Alternative Names
SAP62 antibody
UniProt ID
Q15428
Observed MW
66 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab07775(SF3A2 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab07775(SF3A2 antibody) at dilution of 1:50
Background
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.