SF3A1 antibody

Category: Research Area:
Synonyms：SAP114 antibody
Catalogue No.：FNab07774Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC, IF
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
SF3A1 antibody
Catalogue No.
FNab07774
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
splicing factor 3a, subunit 1, 120kDa
Alternative Names
SAP114 antibody
UniProt ID
Q15459
Observed MW
120-130 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab07774(SF3A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab07774(SF3A1 antibody) at dilution of 1:400
Background
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
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