SESN3 antibody

Synonyms:SEST3 antibody
Catalogue No.:FNab07761Reactivity:Human
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SESN3 antibody
Catalogue No.
FNab07761
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
sestrin 3
Alternative Names
SEST3 antibody
UniProt ID
P58005
Observed MW
51-59 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07761(SESN3 antibody) at dilution of 1:500
Background
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway(PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2(By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses(By similarity).