Products
SEC61alpha antibody
- Product Name
- SEC61alpha antibody
- Catalogue No.
- FNab07687
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Sec61 alpha 1 subunit
- Alternative Names
- FLJ10578 antibody, Sec61 alpha 2 antibody, SEC61A antibody, SEC61A2 antibody, SEC61alpha antibody
- UniProt ID
- P61619
- Observed MW
- 52 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200-1:2000; IF: 1:10-1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07687(SEC61A2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human kindey using FNab07687(SEC61alpha antibody) at dilution of 1:100
- Background
- The SEC61 complex is a major component of the endoplasmic reticulum(ER) translocation site(PMID: 7720858). This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER.
