Products
SEC13 antibody
- Product Name
- SEC13 antibody
- Catalogue No.
- FNab07677
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SEC13 homolog
- Alternative Names
- D3S1231E antibody, SEC13L1 antibody, SEC13R antibody
- UniProt ID
- P55735
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07677(SEC13 antibody) at dilution of 1:1000
IP Result of anti-SEC13 (IP:FNab07677, 3ug; Detection:FNab07677 1:1000) with HepG2 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab07677(SEC13 Antibody) at dilution of 1:50
- Background
- Functions as a component of the nuclear pore complex(NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream and is regulated by amino acid sensors like SESN2(Probable).
