Products
SCNN1A antibody
- Product Name
- SCNN1A antibody
- Catalogue No.
- FNab07648
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sodium channel, nonvoltage-gated 1 alpha
- Alternative Names
- Alpha ENaC antibody, Alpha NaCH antibody, ENaCa antibody, ENaCalpha antibody, FLJ21883 antibody, SCNEA antibody, SCNN1 antibody, SCNN1A antibody
- UniProt ID
- P37088
- Observed MW
- 65kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
PC-13 cells were subjected to SDS PAGE followed by western blot with FNab07648(SCNN1A Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab07648(SCNN1A Antibody) at dilution of 1:50
- Background
- Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium(and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. It has been reported that full-length SCNN1A protein can be cleaved into 65-and 30-kDa fragments.
