human brain tissue were subjected to SDS PAGE followed by western blot with FNab07643(SCN2B antibody) at dilution of 1:300
Background
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier(By similarity).