Products
SCIN antibody
- Product Name
- SCIN antibody
- Catalogue No.
- FNab07635
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- scinderin
- Alternative Names
- Adseverin antibody, KIAA1905 antibody, SCIN antibody, scinderin antibody
- UniProt ID
- Q9Y6U3
- Observed MW
- 75-80 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab07635(SCIN antibody) at dilution of 1:300
IP Result of anti-SCIN (IP:FNab07635, 4ug; Detection:FNab07635 1:300) with human placenta tissue lysate 2800ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07635(SCIN antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells, using SCIN antibody FNab07635 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Background
- Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes(By similarity).
