Products
SCD antibody
- Product Name
- SCD antibody
- Catalogue No.
- FNab07627
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- stearoyl-CoA desaturase(delta-9-desaturase)
- Alternative Names
- Acyl CoA desaturase antibody, Delta(9) desaturase antibody, FADS5 antibody, Fatty acid desaturase antibody, MSTP008 antibody, SCD antibody, SCD1 antibody, SCDOS antibody, Stearoyl CoA desaturase antibody
- UniProt ID
- O00767
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
rat liver were subjected to SDS PAGE followed by western blot with FNab07627( SCD Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab07627(SCD antibody) at dilution of 1:200
- Background
- Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates(PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids(PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation(By similarity). Plays an important role in body energy homeostasis(By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides(By similarity).
