Products
SAMHD1 antibody
- Product Name
- SAMHD1 antibody
- Catalogue No.
- FNab07592
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SAM domain and HD domain 1
- Alternative Names
- MOP5 antibody
- UniProt ID
- Q9Y3Z3
- Observed MW
- 64-72 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, FC
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07592(SAMHD1 antibody) at dilution of 1:1000
IP Result of anti-SAMHD1 (IP:FNab07592, 3ug; Detection:FNab07592 1:300) with K-562 cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab07592(SAMHD1 antibody) at dilution of 1:50
- Background
- Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
