Products
SAFB antibody
- Product Name
- SAFB antibody
- Catalogue No.
- FNab07578
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- scaffold attachment factor B
- Alternative Names
- HAP antibody, HET antibody, SAFB1 antibody
- UniProt ID
- Q15424
- Observed MW
- 150 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab07578(SAFB Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab07578(SAFB Antibody) at dilution of 1:50
- Background
- Binds to scaffold/matrix attachment region(S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex(consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing(By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter(By similarity). Can inhibit cell proliferation.
