Products
SAE1 antibody
- Product Name
- SAE1 antibody
- Catalogue No.
- FNab07577
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SUMO1 activating enzyme subunit 1
- Alternative Names
- AOS1 antibody, SUA1 antibody, UBLE1A antibody
- UniProt ID
- Q9UBE0
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab07577(SAE1 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab07577(SAE1 Antibody) at dilution of 1:200
- Background
- The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
