Products
RYK antibody
- Product Name
- RYK antibody
- Catalogue No.
- FNab07548
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RYK receptor-like tyrosine kinase
- Alternative Names
- JTK5 antibody, JTK5A antibody, RYK antibody, RYK1 antibody, Tyrosine protein kinase RYK antibody
- UniProt ID
- P34925
- Observed MW
- 68 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07548(RYK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab07548(RYK antibody) at dilution of 1:50
Immunofluorescent analysis of SH-SY5Y cells using FNab07548 ( RYK Antibody) at dilution of 1:50 and Alexa Fluor488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Background
- May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
