Products
RRAGB antibody
- Product Name
- RRAGB antibody
- Catalogue No.
- FNab07488
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Ras-related GTP binding B
- UniProt ID
- Q5VZM2
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab07488(RRAGB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab07488(RRAGB Antibody) at dilution of 1:50
- Background
- Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
