Products
RQCD1 antibody
- Product Name
- RQCD1 antibody
- Catalogue No.
- FNab07487
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RCD1 required for cell differentiation1 homolog(S. pombe)
- Alternative Names
- CNOT9 antibody, RCD1 antibody
- UniProt ID
- Q92600
- Observed MW
- 30-40 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab07487(RQCD1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human small intestine slide using FNab07487(RQCD1 Antibody) at dilution of 1:50
- Background
- Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB-and JUN-dependent transcription. May play a role in cell differentiation(By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T(in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
